Cell Lysis and Disruption Market (By Technique: Reagent-based [Detergent, Enzymatic], Physical Disruption [Mechanical Homogenization, Temperature Treatments, Pressure Homogenization, Ultrasonic Homogenization], By Product: Instruments [Sonicator, High Pressure Homogenizers, Microfluidizer, French Press, Bead Mill, Other Instruments], Reagents & Consumables, Enzymes [Ionic Detergent, Detergent Solutions, Zwitterionic Detergent, Nonionic Detergent], Kits & Reagents; By Cell Type: Yeast/Algae/Fungi, Bacterial Cells, Mammalian Cells, Plant Cells; By Application: Downstream Processing, Protein Isolation, Nucleic Acid Isolation, Cell Organelle Isolation; By End Use: Hospitals & Diagnostic Labs, Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, Cell Banks) - Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 - 2026

Category : Healthcare and Pharmaceuticals | Delivery Format : PDF | Status: Published | Pages : 190


According to Acumen Research and Consulting, the global cell lysis & disruption market is forecasted to grow at striking CAGR around 8.5% over the forecast time frame and reach around US$ 5.8 billion by 2026.

Cell lysis is one of the important steps in biological studies for removing the biological substances and using them to achieve their corresponding study objectives in multiple downstream applications. In many sectors, from pharmaceuticals to food, cosmetics and biotechnology, cell lysis is used. It is performed to break cells open to bypass shear forces that can denature or degrade cell proteins and DNA. A number of methods of effective cell disorders are used to accomplish mechanical homogenization, ultrasound, or chemical disorder with various cell lysis reagents.

The report provides analysis of global Anatomic Pathology market for the period 2015-2026, wherein 2019 to 2026 is the forecast period and 2018 is considered as the base year.

Market Insights

Engineering advances in cellular organel release processes have paved the way for the increased implementation of cell disruption techniques. Because biopharmaceuticals are collected and purified by cells, increased demand would result in a subsequent market growth. Moreover, progress is anticipated to boost progressively in this area in the field of proteomics, metabolomics and personalized medicine. However, the high price of equipment combined with the lack of qualified experts will in some way limit the generation of income. Increased investments in R&D linked to biotechnology, both by different governments and private organisations and the market should be considerably further driven by scholars. Furthermore, the increase in incidence of different illnesses and demand for new treatments is anticipated to stimulate market growth.

Expansion into the biopharmaceutical sector will provide fresh market growth opportunities, because cell lysis and disturbance are part of recovery and purification of biopharmaceuticals. In the course of the bioprocess it will also be expected that the adoption of biotech processes in the pharmaceutical, agricultural and bio-service sectors will drive the market progress. The increase in demand for effective tumor dissociation machinery has resulted to the growth of new microfluidics products. In effective dissociation of tumor tissue in single cells, microfluidic devices are helpful and thereby improve cellular recoach in terms of amount and purity.

High maintenance and costly devices, which could hamper market growth in developing areas, are connected with cell-based studies. Cell-based research should be correctly sustained because, in any event, contamination could hinder the general test or study. High maintenance and heavy costs of equipment, such as ultrasound and homogenization, could therefore be used as restrictive variables for the development of the industry in cell lysis. Problems in the mechanical method to apply at the microscale stage and regulatory compliance are another factor restricting this market's development.

Technique Stance

In this market, main players for extraction of intracellular content traditionally embraced physical disturbance techniques. However, these techniques have now been adopted comparatively less because of the costly and cumbersome equipment necessity. Due to the presence of variability in the device, it is difficult to repeat physical disruptive methods, thereby reducing its penetration on the market. Reagent-based methods, by contrast, don't ruin final products' biological activities, are gentle and ideal for laboratory samples.

Product Stance

In 2018, reagents and consumables represented the biggest proportion of revenues, with enzymes dominating the cell lysis & disturbance industry and expected to develop more quickly in the coming years. Application for the selective discharge of product and regulated lysis, which are biological specific to the method, are factors that attrubulate the estimated share. Because of the specificity of the enzyme, bacterial, plant, yeast and mammalian samples have different kits and enzymes. These enzymes can be sold in a number of shapes.

Cell Type Stance

The most important part in 2018 was the mammalian cell segment and is anticipated to stay dominant in the prediction era. Mammalian cultivation systems are widely used when virals, therapeutic proteins and other recombinant products are bio-produced. Further, 3D mammalian culture systems are expected to be used for stem cell research and cancer research to increase the development of the sector. Because the efficiency of reagents varies according to the type of cell, major companies have specifically produced reagents for mammalian cells. Merck Millipore offers, for example, a variety of mammalian lysis reagents used for mammalian phosphorylated, cytosolic and nuclear protein preparations. Some products are the extraction of CytoBuster protein reagent, the extraction kit for NucBuster protein, the phosphoSafe and the kits for ProteoExtract.

Application Stance

These techniques are widely used to isolate protein and process biopharmaceuticals downstream. Protein isolation includes proteomics, western blotting and immunoprecipitation as key fields of implementation. The demand is anticipated to fuelled the development of the segment for effective and quick lysis methods, which may extract proteins with minimal disintegration or oxidation. Another challenge which has to be resolved by pronouncing studies in this section is the viscosity that results from cell debris and genomic contamination. Advanced bioprocessing reagents and machinery are expected to be developed to facilitate market growth and to complement established disturbance processes.

End Use Stance

The most important market share of academic and research institutions was in 2018. This is because there are a wide range of biotechnology institutes which examine molecular biology and methods for bioprocesses, using protocols for cell lysis. The protocols for the testing and study of the tumorigenicity resulted to significant demand in banking biospecimen for cell disruption techniques. Clinical drug development study is anticipated to drive growth in the coming years.

Regional Stance

Geographically, the market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East and Africa. The biggest share of income in 2018 was represented in North America. Different public initiatives in the U.S. and Canada that promote research into molecular biology, precision medicine and cancer will boost cell lysis and the development of the market for disturbance in this region. Both high private and public spending on target therapies and novel discoveries of drugs are expected to boost demand for the therapy of multiple complex and rare diseases. However, Asia Pacific will be the fastest increasing country in the forecast period, given that important firms in emerging markets are increasingly interested in making greater earnings.

Market Segmentation

Global Cell Lysis and Disruption Market, By Technique

  • Reagent-based
    • Detergent
    • Enzymatic
  • Physical Disruption
    • Mechanical Homogenization
    • Temperature Treatments
    • Pressure Homogenization
    • Ultrasonic Homogenization

Global Cell Lysis and Disruption Market, By Product

  • Instruments
    • Sonicator
    • High Pressure Homogenizers
    • Microfluidizer
    • French Press
    • Bead Mill
    • Other Instruments
  • Reagents & Consumables
  • Enzymes
    • Ionic Detergent
    • Detergent Solutions
    • Zwitterionic Detergent
    • Nonionic Detergent
  • Kits & Reagents

Global Cell Lysis and Disruption Market, By Cell Type

  • Yeast/Algae/Fungi
  • Bacterial Cells
  • Mammalian Cells
  • Plant Cells

Global Cell Lysis and Disruption Market, By Application

  • Downstream Processing
  • Protein Isolation
  • Nucleic Acid Isolation
  • Cell Organelle Isolation

Global Cell Lysis and Disruption Market, By End Use

  • Hospitals & Diagnostic Labs
  • Academic & Research Institutes
  • Pharmaceutical & Biotechnology Companies
  • Cell Banks

Global Cell Lysis and Disruption Market, By Geography

  • North America.
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa (MEA)

The market research study on “Cell Lysis and Disruption Market - Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 - 2026” offers detailed insights on global cell lysis & disruption market segments with market dynamics and their impact. The report also covers basic technology development policies.

It offers an assessment of the recent industry trends for each sub-segment between 2015 and 2026, and anticipates income development at worldwide, regional and nation levels. For this research, ARC segmented the worldwide cell lysis & disruption market report on the grounds various segments.

Key Players & Strategies

Some of the key players are Thermo Fisher Scientific, Inc.; Danaher Corporation; F. Hoffmann-La Roche Ltd; Bio-Rad Laboratories, Inc.; Miltenyi Biotec GmbH; Qiagen NV; Merck KGaA; Becton Dickinson & Company (BD); Microfluidics International Corporation; Claremont BioSolutions, LLC; BioVision, Inc.; Parr Instrument Company; Covaris, Inc.; and Qsonica LLC. Competitive market dynamics arise through strategic initiatives, which include fusion and acquisitions, partnerships and joint ventures. These businesses concentrated on new acquisitions / collaborations for product growth in order to strengthen their market position.

These companies offer a broad variety of products and have a large worldwide distribution system. Small players, particularly in Asian emerging markets, also enter the market. However, the market penetration of fresh entrants will be reduced by strict legislative structure and high quality standards set by market leaders.

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