Downstream Processing Market (By Product: Chromatography Systems; By Technique: Cell Disruption, Solid-liquid separation, Concentration, Purification by Chromatography, Formulation; By Application: Antibiotic Production, Hormone Production, Antibodies Production, Enzyme Production, Vaccine Production) - Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 - 2026

Category : Healthcare and Pharmaceuticals | Delivery Format : PDF | Status: Published | Pages : 180

The global Downstream Processing market is expected to reach above US$ 42,754 Mn by 2026 and is expected to register a CAGR of above 13%.

Downstream processing involves recovery of molecules, impurities and contaminants from a complex mixture. The equipments used in downstream processing covers a wide range of system of various size and complexity.

Market Dynamics

Flourishing biopharmaceutical sector across the globe and wide applicability of downstream processing in drug discovery, development of new vaccines, antibiotics, antibodies, etc. is a major factor expected to drive the global market. Biopharmaceutical sector is gaining traction due to promising results without any side-effects. Pharmaceutical manufacturers are investing heavily in biotechnology and bio-service industry.

Moreover, with continuous development in gene therapy and genetic engineering approach towards development of new monoclonal antibodies and antibodies is expected to further boost the market growth. Gradual increase in number of inpatient in hospitals related to cancer across the globe, high mortality due to unavailability of drugs for specific diseases, along with government investment in biotech research and development activities are other factors positively impact the market growth. The Union Budget in 2017-2018 allocated Department of Biotechnology US$ 333.31 Mn which is an increase of 22% in order to continue implementing the department’s national biotech strategy and target increasing the turnover from the sector to US$ 100 Bn by 2025 from US$ 7 Bn in 2016.

However, stringent government regulation related to product approval and high cost associated to new product is major factors restraining the global downstream processing market growth. In addition, lack of advanced infrastructure in developing country and lack of skilled labor will challenge the market growth.

High investment for R&D activities and development of new downstream processing techniques are factors creating new revenue opportunities for market players over the forecast period. In addition, introduction of new facilities overseas in order to increase the business presence and expand customer base is important factor supporting the growing traction. In 2017, Syngene International Ltd., contract research services arm of Biocon Ltd, set up a drug discovery and development center in Bengaluru for Amgen Inc., a biotechnology company based in the US.

The antibiotic production segment of the global market is expected to account for major revenue share, owing to rising demand for antibodies across the globe. Increasing R&D activities in developing countries and establishment of new robust manufacturing facility that are able to produce high amount of monoclonal antibodies will further support the segment growth

Segment Analysis by Region

The Asia Pacific downstream processing market is expected to witness faster growth, owing to high government spending on development of biotechnology industry. These is an increase in number of patient suffering from chronic diseases, increasing number of contract manufacturing organizations (CMOs), and various product pipelines related to viral vectors, multi-specific monoclonal antibodies, peptides is expected to further support the market growth in this region. India has the second-highest number of US Food and Drug Administration (USFDA)–approved plants, after the USA and is the largest producer of recombinant Hepatitis B vaccine. Out of the top 10 biotech companies in India (by revenue), seven have expertise in bio-pharmaceuticals and three specialize in agri-biotech.

Biopharma is largest sector contributing about 62% of the total revenue followed by bio-services (18 %), bio-agri (15 %), bio-industry (4 %), and bio-informatics contributing (1%).

Major player’s inclination towards untapped market in developing country and approach towards shifting the manufacturing units to developing country is expected to further support the region market growth. During the Vibrant Gujarat Global Summit-2017, 54 MoUs worth US$ 736.1 Mn in the biotechnology sector were signed by 37 companies.

Competitive Landscape

Downstream processing market is highly competitive due to large presence of players operating in market. In addition, high investment by major players for R&D activities will further increase the competition.

Report coverage

The market research study on “Downstream Processing Market (Product: Chromatography Systems, Filters, Evaporators, Centrifuges, Dryers, and Consumables and Accessories; Technique: Cell Disruption, Solid-liquid separation, Concentration, Purification by Chromatography, and Formulation; Application: Antibiotic Production, Hormone Production, Antibodies Production, Enzyme Production, and Vaccine Production) – Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 - 2026”, offers a detailed insights on the global downstream processing market entailing insights on its different market segments. Market dynamics with drivers, restraints and opportunities with their impact are provided in the report. The report provides insights on global downstream processing market by product, technique, application segment and major geographic regions. The report covers basic development policies and layouts of technology development processes. Secondly, the report covers global downstream processing market size and segment markets by product, technique, application, and geography along with the information on companies operating in the market. The downstream processing market analysis is provided for major regional markets including North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. For each region, the market size for different segments has been covered under the scope of report. The players profiled in the report include General Electric Company, Thermo Fisher Scientific Inc., Merck KGaA, Sartorius Stedim Biotech S.A., Danaher Corporation, Dover Corporation, Repligen, Boehringer Ingelheim International GmbH, 3M Company, Eppendorf AG, Corning Corporation, Ashai Kasei, Lonza Group Ltd, and Ferner PLC.

Market Segmentation

Market By Product

Chromatography Systems

  • Filters
  • Evaporators
  • Centrifuges
  • Dryers
  • Consumables and Accessories

Market By Technique

Cell Disruption

Solid-liquid separation

  • Filtration
  • Centrifugation


  • Evaporation
  • Membrane filtration

Purification by Chromatography


Market By Application

  • Antibiotic Production
  • Hormone Production
  • Antibodies Production
  • Enzyme Production
  • Vaccine Production

Market By Region

North America

  • US
  • Canada


  • UK
  • Germany
  • France
  • Spain
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Mexico
  • Rest if Latin America

Middle East & Africa

  • GCC
  • South Africa
  • Rest of Meddle East & Africa

Frequently Asked Questions

The global downstream processing market in 2018 was above US$ 42,754 Mn.

In the product segment the consumables and accessories segment is growing at faster pace.

The CAGR of the global downstream processing market from 2019-2026 is above 13%.

Among the application segment the antibiotic production segment accounts for high revenue share.

Some of the players considered in the report scope are General Electric Company, Thermo Fisher Scientific Inc., Merck KGaA.

Asia Pacific is projected to grow at a fast pace during forecast period in the downstream processing market.

The global downstream processing market is segmented into the product, technique, application segment and major geographic regions.

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