Peptide Synthesis Market By Product (Reagents & Consumables, Equipment, Others), By Technology (Solid Phase, Liquid Phase, Hybrid Phase), By End-User (Therapeutics, Diagnosis, Research) - Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 – 2026

Category : Chemicals and Materials | Delivery Format : PDF | Status: Published | Pages : 190

The global peptide synthesis market is expected to grow at significant CAGR of 6.6% over the forecast period 2019 to 2026 and reach around more than USD 400 million by 2026.

Peptides are organic molecules of a peptide (amide) bound amino acids. Peptide synthesis is the mechanism by which a carboxylic acid from one amino acid is compressed into the amino group of another, forming short sequences of peptides. The production of advanced peptide synthesizers is expected to drive market growth, such as increased use of peptides in pharmaceutical medicinal products, increased research activities, and availability of funds for R & D. The lack of a standardized set of rules for therapeutic peptides, however, is expected during the forecast period to limit the growth of this market.

While chemical synthesis is the most mature technology to synthesize peptide, lacking specificity and environmental impact are serious disadvantages that enzyme biocatalysis can in theory succeed in overcoming. Nonetheless, enzyme synthesis efficiency is lower. Biocatalyst cost is usually high and no validation and expansion protocols exist that reflect challenges which are actively faced by intensive research and development in this field.

Market Insights

To carry out the coupling reactions, multiple reagents are added to activate the amino acid carboxyl groups. Most of them include hydroxybenzotriazole (HOBT), phosphonium salts, and uranium. N-methylpirrolidone, dimethylacetamide, Chaotropic salts, and mixture of solvents are used in difficult sequences to improve binding performance and the elongation of the peptide chain. Sequence synthesis, chemical binding, and convergent synthesis are the main solid phase peptide synthesis (SPPS) techniques.

Cells need a variety of chemical subsystems, including functionally supported peptides, split lipids and many small other molecules that form the basis of metabolization.

All species contain 7,000 natural peptides that have a large role in the biology of bacteria, plants, animals and people. Peptides and proteins are well known to be highly specific and powerful to their natural aim and to have a good human safety profile. This makes them a great choice for developing new biopharmaceutical products. Unmodified peptides and proteins often have short half-lives in blood due to kidney clearance, proteolytic degradation or specific absorption by the receptor. Synthetic peptides are rapidly growing. Such molecules are commonly used for work in biomedicine, biology, or the cosmetics industry. The peptide pharmaceuticals market today stands at USD 15 billion. The downside of peptide processing is the vast amounts of toxic organic solvents (DCM) and DIMF, used in significant abundance for both solvent syntheses and solid-phase peptide synthesis.

Major Classes Of Peptides

Class

Source

Application

Ribosomal Peptides

mRNA translation

Antibiotics, Hormones,

Signaling peptides, Bacteriocins

Non-Ribosomal Peptides

Non-ribosomal peptide synthetases

Toxins, Cytostatics, Siderophores, Pigments, Antibiotics, Immunosuppressants

Peptones

Enzymatic digestion or acid hydrolysis of natural products

Ingredient in bacterial and fungal growth media

Peptide Fragments

Degradation of forensic or paleontological samples by natural effects

Identification or quantification of the source protein


Product and Technology Insights

Convergent synthesis involves the independent synthesis of the peptide sequences, which are connected in the liquid phase by condensation. Many checks must be performed during the peptide synthesis cycle at medium, but mostly to the final product. The ninhydrin test is the most common test of free amino groups due to its tolerance and reproducibility. Enzymes are the cell activation biology catalysts. As such, they need to perform well under the mild cell operating conditions. They must be robust enough to meet harsh conditions of an industrial process, usually involving modification of the enzyme to produce a stable biocatalyst, to become process biocatalysts.

Extensive studies aimed at producing new equipment for peptide synthesis have contributed to this segment's most rapid growth in the global market. The term solid phase peptide synthesis is misleading and gel-phase synthesis is more suitable. In the coming years, recent developments concerning peptide coupling reagents are expected to boost market growth.

End Use Outlook  

Based on end-use the market has e been segmented into therapeutics, diagnosis, and research. Therapeutics segmented has dominated the global end-use market in terms of revenue and is likely to maintain similar trend over the forecast period. Furthermore, diagnosis segment is projected to display fastest growth over the forecast period. Synthesized peptides are commonly used for cancer therapy and have made this segment a significant contributor to therapeutic revenue. Advancement in the manufacturing of peptides that play a key role in metabolic regulations should offer useful insights into the development of effective treatment approaches. Robust growth of the Peptide Therapeutics industry is a key driver for the dominance of end-use companies in the global pharmaceutical & biotechnology market.

Regional Snapshots

In terms of region the global peptide synthesis market is segmented into North America, Europe, Asia Pacific, Central & South America, and Middle East & Africa. Asia Pacific is anticipated to be the fastest growing region over the foreseeable future. Increasing investment by players across outskirts of Asia Pacific coupled with economies of scale is projected to be the key factor for the optimistic market of peptide synthesis across this region.

North America made the most important contribution to the global market, due to the strong presence of major players in the industry, increased awareness of the available peptide synthesis technology and the increasing emphasis on commercially moving peptide products.

Report coverage

The market research study on Peptide Synthesis Market: by Product (Reagents & Consumables, Equipment, Others), Technology (Solid Phase, Liquid Phase, and Hybrid Phase), End User (Therapeutics, Diagnosis, and Research), Geography (North America, Europe, Asia Pacific, Central & South America, Middle East & Africa):-Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 – 2026” offers a detailed insights on the global peptide synthesis market entailing insights on its different market segments. Market dynamics with drivers, restraints and opportunities with their impact are provided in the report. The report provides insights on global peptide synthesis market, its ingredient, product, and major geographic regions. The report covers basic development policies and layouts of technology development processes. Secondly, the report covers global peptide synthesis market size and volume, and segment markets by ingredient, product, and geography along with the information on companies operating in the market. The Peptide Synthesis market analysis is provided for major regional markets including North America, Europe, Asia-Pacific, Latin America, Middle East and Africa. For each region, the market size and volume for different segments has been covered under the scope of report.

Key Players and Strategies

Key players in this market comprise of Bachem Holdings, Biotage, Thermo Fisher, Polypeptide Group, PuroSynth, Syngene, MP Biomedicals, Novo Nordisk A/S, Genscript Biotech, Merck KGaA, etc

The global Peptide Synthesis market is segmented as below:

Market Segmentation

Market By Product

  • Reagents & Consumables
  • Equipment
  • Others

Market By Technology

  • Solid Phase
  • Liquid Phase
  • Hybrid Phase

Market By End-User

  • Therapeutics
  • Diagnosis
  • Research

Market By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa


Related Reports

Chemical Tanker Shipping Market (By Types: Inland Chemical Tankers (1,000-4,999 DWT), Coastal Chemical Tankers (5,000-9,999 DWT), Deep-Sea Chemical Tankers (10,000-50,000 DWT); By Application: Organic Chemicals, Inorganic Chemical, Vegetables Oils & Fats, Others (Additives, Lube Oils, and Molasses)) – Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 - 2026

The global chemical tanker shipping market is expected to grow at a CAGR of around 5.7% from 2019 to 2026 and expected to reach the market value of around US$ 250,562.6 Mn by 2026. Chemical tanker shipping refers to the constructed ships for carrying liquid chemicals in bulk. These chemical tankers are required to fulfill safety aspects because many chemicals are flammable and toxic. Additionally, these tankers are required mandatory comp

Specialty Chemicals Market (By Type: Specialty Oilfield Chemicals, Pesticides, Construction Chemicals, Specialty Polymer, Food Additives, Others; By FunctionL: Biocides, Surfactants, Antioxidants, Others) - Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 - 2026

The global specialty chemicals market is expected to reach value of around US$ 301 Bn by 2026 and is anticipated to grow at a CAGR of around 4.8% in terms of revenue during the forecast period 2019 to 2026. Specialty chemicals are special type of chemicals which are produce as per the requirement of diverse industry sectors such as cosmetic, food, textile, construction chemical etc. A complex, interlinked indu

Nitrile Butadiene Rubber (NBR) Latex Market (By Product: Medical Grade, Industrial Grade; By End-User: Medical, Industrial) –Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 - 2026

The global nitrile butadiene rubber (NBR) latex market value is expected to reach around US$ 2860.1 Mn by 2026, growing at a CAGR of 15.4% over the forecast period 2019 to 2026. Nitrile butadiene rubber (NBR) latex is a type of synthetic latex in liquid form with milky color. It’s a part of unsaturated acrylonitrile and butadiene copolymers family. NBR latex properties include excellent tensile strength

Peptide Synthesis Market By Product (Reagents & Consumables, Equipment, Others), By Technology (Solid Phase, Liquid Phase, Hybrid Phase), By End-User (Therapeutics, Diagnosis, Research) - Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 – 2026

The global peptide synthesis market is expected to grow at significant CAGR of 6.6% over the forecast period 2019 to 2026 and reach around more than USD 400 million by 2026. Peptides are organic molecules of a peptide (amide) bound amino acids. Peptide synthesis is the mechanism by which a carboxylic acid from one amino acid is compressed into the amino group of another, forming sh

Recycled Glass Market By Sources (Deposit, Buy Back/Drop-Off, Curbside), By Product (Cullet, Crushed Glass, Glass Powder), By Application (Glass Bottle & Containers, Flat Glass, Fiber Glass, Highway Beads, Abrasives, Fillers, Others) – Global Industry Analysis, Market Size, Opportunities And Forecast, 2019 - 2026

The global recycled glass market value is expected to reach around 5,723.6 million by 2026 and will grow at a CAGR of 6.0% over forecast period 2019 to 2026. Recycled glass refers to the reusing glass objects, which are preferably used for making virgin glass. The recycling of glass is a cost-effective process of virgin glass production, because it conserves natural resources, saves energy and simple to recycl

Electric Vehicle Polymers Market By Type (Engineering Plastics, Elastomers, Others), By Component (Powertrain System, Exterior, Interior, Others), By Application (Passenger Electric Vehicles, Commercial Electric Vehicles) – Global Industry Analysis, Market Size, Opportunities And Forecast, 2019-2026

The global electric vehicle polymers market size is expected to reach around 159 billion by 2026 growing at a CAGR of around 64.9% over forecast period 2019 to 2026. Electric Vehicle Polymers refers to the polymers used in electric cars for the increasing the efficiency of the vehicle by reducing the weight of the vehicle. Polymers resemble the characteristics of metals such as better flame retardancy, toughne

Cart Summary